Ankle/Foot pain DDx

Ankle and Foot pain – Differential Diagnosis

Common causes

Must Not Miss

Easily missed

Red flags

  • Not weight-bearing
  • Cold pulse-less leg
  • Back pain & Loss of bladder or bowel control
  • Hot/painful/swollen joint with little movement
  • Sudden severe achilles pain with foot drop
  • Ulceration/cellulitis
  • Systemic symptoms (fever, weight loss)

Investigations to consider

  • FBC, CRP/ ESR, serum glucose
  • Auto-antibody screen, Rheumatoid factor
  • Serum uric acid
  • Local X-ray
  • Blood culture
  • MRI scan
  • Nerve conduction studies
  • Bone scan
  • Angiography

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