Bleeding & Bruising DDx

Bleeding & Bruising – Differential Diagnosis

Common causes

Must Not Miss

Easily missed

Red flags

  • Sepsis
  • Petechial rash of meningitis
  • Systemic symptoms
    • (fever, weight loss, lethargy, bone pain)
  • Symptoms of anaemia

Investigations to consider

  • FBC + film, CRP/ESR, clotting screen
  • U+Es, LFTs, LDH
  • Myeloma screen
  • Auto-antibody screen
  • Urinalysis
  • CXR
  • CT scan (Head, chest, abdomen & pelvis)
  • Lumbar Puncture
  • Bone scan
  • Bone marrow analysis