Calf pain DDx

Calf pain – Differential Diagnosis

Common causes

Must Not Miss

Easily missed

Red flags

  • Cold pulseless leg
  • Unilateral pain/tenderness and swelling
  • Risk factors for DVT
  • Swelling of the entire leg
  • Acute chest pain, Dyspnoea or Haemoptysis
  • Severe progressive pain
  • Systemic symptoms (fever, weight loss)
  • Immunosuppression

Investigations to consider

  • FBC, CRP/ESR, D-dimer
  • U&Es, LFTs, Blood glucose, bone profile
  • Local X-ray
  • Duplex USS
  • Venography
  • Angiography
  • MRI scan (lumbar spine)